CUDA

CUDA is NVIDIA's GPU-compute platform and the de facto standard most AI software targets first. Its ubiquity is the recurring theme in this catalog's trade-offs: the NVIDIA GB10 boxes (DGX Spark, ASUS Ascent GX10) are 'CUDA-native,' while every AMD Strix Halo box and every Apple Mac is flagged 'no CUDA' — meaning some tools assume NVIDIA and need a workaround elsewhere. On AMD you fall back to ROCm or Vulkan; on Apple you use MLX or Metal. For mainstream models via Ollama or LM Studio this rarely bites, but niche or cutting-edge tooling often ships CUDA-first.

CUDA compatibility is much of what you're paying the premium for on a GB10 box. If your workflow depends on a CUDA-only library, that decides the platform; if you live in Ollama/LM Studio, AMD and Apple are fine.